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This educational activity is certified by the American College of Cardiology Foundation
Detection of High-Risk Atherosclerotic Plaque (JACC: Cardiovascular Imaging)
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JACC Cardiovascular Imaging Editor-in-Chief
Jagat Narula, MD, PhD, FACC

Ragaven Baliga, MD

Jerome L. Fleg, MD

Gregg W. Stone, MD

Zahi A. Fayad, PhD

Juan F. Granada, MD

Thomas S. Hatsukami, MD, PhD

Frank D. Kolodgie, PhD

Jacques Ohayon, PhD

Roderic Pettigrew, MD, PhD

Marc S. Sabatine, MD

Guillermo J. Tearney, MD, PhD

Sergio Waxman, MD

Michael J. Domanski, MD

Pothur R. Srinivas, PhD

Jagat Narula, MD, PhD




This article appeared in the September 10, 2012 issue of JACC: Imaging Journal.


This online educational activity is brought to you by JACC: Cardiovascular Imaging.

CME Information

Target Audience

JACC Journals CME is intended for physicians who treat patients with cardiovascular disease.

Important Dates

Date of Release: September 2012

Term of Approval/Date of CME Expiration: September 2013

Learner Objectives

At the completion of this article, the learner should be able to discuss:

  • The significance of the vulnerable plaque, particularly thin-cap fibroatheroma, in the pathogenesis of acute myocardial infarction.
  • The role of invasive and noninvasive imaging modalities in the detection of high risk coronary lesions
    and high risk patients.
  • The utility of novel biomarkers and genetic profiling in the identification of patients who are most likely to benefit from noninvasive imaging for vulnerable plaques, and from invasive imaging for risk confirmation.
  • The future role of imaging and biomarkers in determining appropriate pharmacologic and/or device based focal or regional therapies.

Method of Participation and Claiming Credit
This ACCF JACC Journals CME activity includes the reading of an article published in one of the JACC journals and the successful completion of self-assessment questions.

Requesting AMA PRA Category 1 CME Credit™ for this Activity
To request credit, you must:

  1. Read the article for which you wish to receive credit.
  2. Answer the self-assessment questions. After you have answered all the questions in the module, click on the Exam Summary button. A Claim Credit button will appear on this page if you have achieved a passing score of 66% or better. If you did not achieve a passing score, please click the Reset Scores link and retake the exam.
  3. Click the Claim Credit button and answer the evaluation questions in the pop-up window.
  4. Enter the total amount of time you actually spent in the activity in the box provided. Please note that you may only claim once for this activity. Click Submit.
  5. You will receive a message that your request has been submitted and a link to view your certificate. You may download the certificate when you receive the message.
  6. You may also view it at any time in the My Transcript section of My CardioSource.