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This educational activity is certified by the American College of Cardiology Foundation
Drug–Drug Interactions in Cardiovascular Catheterizations and Interventions (JACC: Cardiovascular Interventions)
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JACC: Cardiovascular Interventions Editor-in-Chief

Spencer B. King III, MD, MACC

JACC: Cardiovascular Interventions CME Editor

Habib Samady, MB, ChB, FACC


Steven P. Dunn, PharmD

David R. Holmes Jr., MD, FACC

David J. Moliterno, MD, FACC



This article appeared in the December 17, 2012 issue of JACC: Cardiovascular Interventions Journal.


This online educational activity is brought to you by the JACC family of Journals.

CME Information

Target Audience

JACC Journals CME is intended for physicians who treat patients with cardiovascular disease.

Important Dates

Date of Release: December 2012

Term of Approval/Date of CME Expiration: December 2013

Learner Objectives

At the completion of this article, the learner should be able to discuss:

  • The potential for drug-drug interactions among patients undergoing invasive cardiovascular procedures as well as the primary mechanism: altered pharmacokinetics or altered pharmacodynamics.
  • The mechanism to evaluate the likelihood that a drug interaction is actual and meaningful should be appreciated.
  • The leading drugs potentially at risk for altered activity and how these might affect procedural or long-term outcome such as increased risk for thrombosis or hemorrhage.

Method of Participation and Claiming Credit
This ACCF JACC Journals CME activity includes the reading of an article published in one of the JACC Journals and the successful completion of self-assessment questions.

Requesting AMA PRA Category 1 CME Credit™ for this Activity
To request credit, you must:

  1. Read the article for which you wish to receive credit.
  2. Answer the self-assessment questions. After you have answered all the questions in the module, click on the Exam Summary button. A Claim Credit button will appear on this page if you have achieved a passing score of 66% or better. If you did not achieve a passing score, please click the Reset Scores link and retake the exam.
  3. Click the Claim Credit button and answer the evaluation questions in the pop-up window.
  4. Enter the total amount of time you actually spent in the activity in the box provided. Please note that you may only claim once for this activity. Click Submit.
  5. You will receive a message that your request has been submitted and a link to view your certificate. You may download the certificate when you receive the message.
  6. You may also view it at any time in the My Transcript section of My CardioSource.