Tuesday March 27 2012

• CardioSource Video News

  • View Meeting Highlights  

• Moderate Pulmonary Embolism Treated with Thrombolysis (MOPETT Study)

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Low-Dose Thrombolysis Eases PE  

• Results of the IMMEDIATE (Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care) Trial: A Double-Blind Randomized Controlled Trial of Intravenous Glucose, Insulin, and Potassium (GIK) for Acute Coronary Syndromes in Emergency Medical Services

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Metabolic Support May Only Mitigate MI  

• Multicenter Randomized Comparative Effectiveness Trial of Cardiac CT vs Alternative Triage Strategies in Acute Chest Pain Patients in the Emergency Department: Results from the ROMICAT II Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  

• Survival after PCI or CABG in Older Patients with Stable Multivessel Coronary Disease: Results from the ACCF-STS Database Collaboration on the Comparative Effectiveness of Revascularization Strategies (ASCERT)

  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Bypass Surgery Bests Stents in Real-World Survival  

Monday March 26 2012

• CardioSourceNews

  • Read the Monday Edition  

• Pacemaker Therapy In Patients With Neurally-mediated Syncope And Documented Asystole (ISSUE3)

  • Trial Summary  
  • Presentation Slides  
  • Fainting Spells Cut with Cardiac Pacing  

• Comparison of Bariatric Surgical Procedures and Advanced Medical Therapy for the Treatment of Type 2 Diabetes in Patients with Moderate Obesity: 1 Year STAMPEDE Trial Results

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Surgery Bests Drugs for Obese Diabetics  

• A Mendelian Randomized Controlled Trial of Long Term Reduction in Low-Density Lipoprotein Cholesterol Beginning Early in Life

  • Presentation Slides  
  • Earlier LDL Focus Could Be Beneficial  

• A Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, REGN727/SAR236553, in Patients with Primary Hypercholesterolemia (NCT: 01288443)

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Biologic Wows for Lipid Lowering  

• ACRIN PA 4005: Multicenter Randomized Controlled Study of a Rapid "Rule Out" Strategy Using CT Coronary Angiogram Versus Traditional Care for Low-Risk ED Patients with Potential Acute Coronary Syndromes

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Coronary CTA Trumps Usual ED Triage for Chest Pain  

• CORONARY: The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Beating-Heart Bypass No Clear Winner  
  • CABG On-Pump or Off Equal  

• Oral Rivaroxaban Alone for Symptomatic Pulmonary Embolism: the EINSTEIN PE Study

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Standard in PE Met by Rivaroxaban  

• Late (≥ 2 year) Clinical and Echocardiographic Outcomes after Transcatheter vs. Surgical Aortic Valve Replacement: Results from the High-Risk Cohort of The PARTNER Cohort A Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • TAVI Results Persist over Two Years  

Sunday March 25 2012

• A Multifaceted Intervention to Narrow the Evidence-Based Gap in the Treatment of Acute Coronary Syndromes: Main Results from the BRIDGE-ACS Cluster Randomized Trial

  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Reminders, Checklists Enhance Acute Care  

• Outcomes of Non-Primary PCI at Hospitals With and Without On-site Cardiac Surgery: CPORT-E Trial. Final Medical Outcomes

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Elective PCI Safe Without Surgical Backup  
  • Non-Primary PCI OK at Centers Without Surgical Safety Net  

• Randomized Comparison of Adding Cilostazol Versus Doubling the Dose of Clopidogrel After Receiving Percutaneous Coronary Intervention: The HOST-ASSURE Randomized Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Three Equals Two in Antiplatelet Regimen  

• INFUSE-AMI: A 2x2 Factorial, Multicenter, Prospective, Randomized Evaluation of Intracoronary Abciximab and Aspiration Thrombectomy in Patients Undergoing Primary PCI for Anterior STEMI

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  
  • Journal Scan  
  • Reopro Shrinks Infarct Size in STEMI  

• CardioSourceNews

  • Read the SUNDAY Edition  

Saturday March 24 2012

• Late Benefit of Intra-Aortic Balloon Counterpulsation during High-risk Percutaneous Coronary Intervention: Long-term Mortality Data from the Balloon pump-assisted Coronary Intervention Study (BCIS-1)

  • Trial Summary  
  • Presentation Slides  

• A Prospective Randomized Study Using Optical Coherence Tomography to Assess Endothelial Coverage and Neointimal Proliferation at 6 Months After Implantation of a Coronary Everolimus-Eluting Stent compared with a Bare Metal Stent postdilated with a Paclitaxel-Eluting Balloon (OCTOPUS Trial)

  • Presentation Slides  

• Sirolimus Eluting Stent with Biodegradable Polymer Versus Sirolimus Eluting Stent with Durable Polymer for the Treatment of Patients with de novo Coronary Artery Lesions (EVOLUTION): a Randomized Non-inferiority Trial

  • Presentation Slides  

• Biodegradable Polymer Drug-Eluting Stents Versus Durable Polymer Sirolimus-Eluting Stents in Patients Undergoing Percutaneous Coronary Intervention: A Pooled Analysis of Individual Patient Data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS Randomized Trials at 4 Years

  • Presentation Slides  

• 2 Year Clinical Outcomes from the Pivotal RESOLUTE US Study

  • Presentation Slides  

• Visual-Functional Mismatch between Coronary Angiography and Fractional Flow Reserve

  • Presentation Slides  

• Evaluation of a Novel Antiplatelet Agent for Secondary Prevention in Patients With Atherosclerotic Disease: Results of the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events TRA 2P–TIMI 50 Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video 1  
  • CardioSource Video 2  
  • Journal Scan  
  • Events Cut, but Bleeding Up with Novel Drug  

• Effect of Transendocardial Autologous Bone Marrow Mononuclear Cell Delivery on Functional Capacity, Left Ventricular Function and Perfusion in Chronic Ischemic Heart Failure: The FOCUS-CCTRN Randomized Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video 1  
  • CardioSource Video 2  
  • Journal Scan  
  • Stem Cells Flop in Heart Failure Study  

• A New Strategy for Discontinuation of Dual Antiplatelet Therapy: Real Safety and Efficacy of 3 Months Dual Antiplatelet Therapy Following Endeavor Zotarolimus-Eluting Stent Implantation: RESET Trial

  • Trial Summary  
  • Presentation Slides  
  • CardioSource Video  

• Treatment of High Risk Aortic Stenosis Patients with Transcatheter Medtronic CoreValve Implantation: Results from the International Multi-center ADVANCE Study

  • Presentation Slides  
  • CardioSource Video  
  • TAVI Valves Safe, Durable  

• A Double Blind Randomized Study to Evaluate the Efficacy of Bindarit in Preventing Coronary Stent Restenosis

  • Presentation Slides  

• First Pharmacogenomic Analysis Using Whole Exome Sequencing to Identify Novel Genetic Determinants of Clopidogrel Response Variability: Results of The Genotype Information and Functional Testing (GIFT) EXOME Study

  • Presentation Slides  

• Pharmacodynamic Effects of Switching Therapy in PCI Patients with High on Treatment Platelet Reactivity and Genotype Variation: High Clopidogrel Dose versus Prasugrel (RESET Study)

  • Presentation Slides  

• Long-Term Outcomes Following Transcatheter Aortic Valve Implantation: Insights on Prognostic Factors and Valve Durability from the Canadian Multicenter Experience

  • Presentation Slides  
  • TAVI Valves Safe, Durable  
  • TAVI Deaths Mostly Noncardiac  

Friday March 23 2012

• CardioSourceNews

  • Preview the SATURDAY Edition  

• Antiplatelet, Antibody Big Draws at ACC

  CHICAGO — An investigational antiplatelet for patients with stable ischemic heart disease and a monoclonal antibody designed to lower LDL cholesterol levels are among the hot topics that will be presented here at the American College of Cardiology meeting.

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