TCT: Transcatheter Cardiovascular Therapeutics

November 7-11, 2011 - San Francisco, CA

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Wrap-up of TCT 2011

Dr. Peter Block discusses the highlights of science presented at TCT 2011.
- CardioSource Video

Genetic Tests, Stent Thrombosis Highlight Meeting

SAN FRANCISCO — With more than 22 late-breaking trials, 650 abstracts, 100 live cases, and more than 3,000 presentations, the 12,000 people in attendance at this year's Transcatheter Cardiovascular Therapeutics meeting had a lot to choose from.
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Longitudinal Stent Compression Needs More Study

SAN FRANCISCO — Longitudinal stent compression is rare and most often used in complex cases by operators experienced in the technique, but more research is needed to assess its potential effects, according to researchers here.
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Uptake of DAPT After Stenting Unclear

SAN FRANCISCO — Research continues to assess the optimal duration and potential for customization of dual antiplatelet therapy for stented patients, but it's unclear whether results of recent studies are being put into practice, Roxana Mehran, MD, explains in this exclusive InFocus report.
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Newest Stents Cut Polymer Threat

SAN FRANCISCO — A pair of experimental third-generation stents with minimized amounts of polymer coating are at least noninferior to previous stents in early trials, researchers reported here.
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Combo Stent Comparable to Taxus

SAN FRANCISCO — A combination stent that incorporates an antiproliferative drug and an agent that promotes healing works as well as a paclitaxel-eluting stent, researchers reported here.
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New Pressure Index Is FFR Minus Adenosine

SAN FRANCISCO — A new pressure-based index to measure the severity of coronary lesion stenosis without adenosine compared favorably to fractional flow reserve (FFR) with adenosine, researchers found.
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PROFI

A Prospective, Randomized Trial of Proximal Balloon Occlusion vs. Distal Filter Embolic Protection in Patients Undergoing Carotid Stenting
- Trial Summary
- Presentation Slides
COBRA

A Prospective, Randomized Trial of Cryoplasty vs. Conventional Balloon Post-dilatation of Nitinol Stents in the Superficial Femoral Artery of Patients with Diabetes Mellitus
- Trial Summary
- Presentation Slides
TWENTE

A Prospective, Randomized Trial of Zotarolimus-Eluting Stents and Everolimus-Eluting Stents in an Unselected Patients with Coronary Artery Disease
Longitudinal Stent Compression Rare but Not Deadly

SAN FRANCISCO — The publication of a few case reports has brought longitudinal stent compression into the spotlight, and interventional cardiologists need to be aware of the issue, says Ajay Kirtane, MD, in this exclusive InFocus video report.
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Access Site Drives TAVI Costs, Quality

SAN FRANCISCO — Compared with surgery, quality of life was significantly improved for patients undergoing transcatheter aortic valve implantation (TAVI) from a transfemoral approach, but no such effect was seen in those undergoing TAVI from a transapical approach, researchers here reported.
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MUSTELA

A Prospective, Randomized Trial of Thrombectomy vs. No Thrombectomy in Patients with ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesions
- Trial Summary
- Presentation Slides
RIFLE STEACS

A Prospective, Randomized Trial of Radial vs. Femoral Vascular Access in Patients with ST-Segment Elevation Myocardial Infarction
STACCATO

A Prospective, Randomized Trial of Transapical Transcatheter Aortic Valve Replacement vs. Surgical Aortic Valve Replacement in Low-Surgical-Risk Elderly Patients with Aortic Stenosis
- Trial Summary
- Presentation Slides
PARTNER Cohort B Two-Year

A Prospective, Randomized Trial of Transcatheter Aortic Valve Replacement vs. Standard Therapy in Patients with Inoperable Aortic Stenosis
DAPT Adherence Good Early On

SAN FRANCISCO — Patients are sticking to the plan when it comes to dual antiplatelet therapy (DAPT), but not adhering to the regimen is still associated with an increased risk of stent thrombosis, even in the short term, researchers said here.
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BRIDGE

A Prospective, Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial of Intravenous Cangrelor in Patients Awaiting Surgery
TRIGGER-PCI

A Prospective, Randomized Trial of Prasugrel vs. Clopidogrel in Clopidogrel-Hyporesponsive Patients with Stable Ischemic Heart Disease Undergoing Percutaneous Coronary Intervention
- Trial Summary
- Presentation Slides
RAPID GENE

A Prospective, Randomized Trial of Prasugrel vs. Clopidogrel in CYP2C19*2 Carriers Identified by Rapid Point-of-Care Genotyping
ADAPT-DES

Platelet Responsiveness and Stent Thrombosis After DES Implantation
Finding the 'Sweet Spot' for Dual Antiplatelet Therapy

SAN FRANCISCO — Customizing antiplatelet regimens to fit individuals should improve outcomes for drug-eluting stents, but even as stent technology has progressed, finding the 'sweet spot' for dual antiplatelet therapy remains elusive, researchers here explain in the exclusive video report.
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Women Face Bleeding Over Long Term Post-MI

SAN FRANCISCO — Aside from poorer outcomes immediately following MI, women also fare worse than men in the long run, researchers said here.
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LEADERS

Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial
- Trial Summary
- Biodegradable Stent Effective at Four Years
Team Work Replaces Turf Wars in Heart Disease

SAN FRANCISCO — Cooperation is rapidly replacing competition in the cardiovascular world as both surgeons and interventionalists are signing on to the "heart team" for treatment of patients with stable coronary disease as interventional cardiologist J. Jeffrey Marshall, MD, explains in this exclusive InFocus video report on the American College of Cardiology/American Heart Association revascularization guidelines.
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Access Location Doesn't Change Radiation Exposure

SAN FRANCISCO — Transradial access for angiography or stenting does not increase patients' radiation exposure compared with femoral access, researchers said here.
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Risk Model Predicts PCI Outcome

SAN FRANCISCO — A risk assessment score that uses age, creatinine level, and ejection fraction (ACEF) was a good predictor of death in patients undergoing PCI in routine clinical practice, researchers found.
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Full Plate of Late-Breakers on Tap in San Francisco

SAN FRANCISCO — At this year's Transcatheter Cardiovascular Therapeutics meeting, there are some 20 late-breaking trial presentations with more than a few with the potential to impact clinical practice if the results are positive.
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