Clinical Trials

Featured Clinical Trials

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  Title:	International Randomized Comparison Between DES Limus Carbostent and Taxus Drug-Eluting Stents in the Treatment of De Novo Coronary Lesions
  Year:	2012

  Summary Slide(s):	NEXT Summary Slide
  Clinical Trial:	Limus Eluted From A Durable versus ERodable Stent coating
  Clinical Trial:	SPIRIT
  Clinical Trial:	Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients With de Novo Native Coronary Artery Lesions
  Clinical Trial:	Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions
  Clinical Trial:	Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System IV
  Journal Scan:	A Multicenter Randomized Trial Comparing Amphilimus- With Paclitaxel-Eluting Stents in De Novo Native Coronary Artery Lesions

• PROFI
  Title:	Prevention of Cerebral Embolization by PROximal Balloon Occlusion Compared to FIlter Protection During Carotid Artery Stenting
  Year:	2012

  Summary Slide(s):	PROFI Summary Slide (Updated)
  Clinical Image:	PROFI Presentation Slides
  Journal Scan:	The PROFI Study (Prevention of Cerebral Embolization by Proximal Balloon Occlusion Compared to Filter Protection During Carotid Artery Stenting): A Prospective Randomized Trial
  Cardiosource Video News:	Balloon or Filter Protection for Carotid Stenting?

• FAME II
  Title:	Fractional Flow Reserve-Guided Percutaneous Coronary Intervention Plus Optimal Medical Treatment (OMT) vs. OMT Alone
  Year:	News Release: 2012

  Clinical Trial:	Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation
  Clinical Trial:	Fractional Flow Reserve Versus Angiography for Multivessel Evaluation
  Cardiosource Video News:	Afib Risk, FAME II, and Lifetime Risk of CV Disease

• BRIDGE
  Title:	Maintenance of Platelet Inhibition With Cangrelor After Discontinuation of Thienopyridines in Patients Undergoing Surgery
  Year:	2012

  Summary Slide(s):	BRIDGE Summary Slide
  Clinical Image:	BRIDGE Presentation Slides
  Cardiosource Video News:	RAPID GENE and BRIDGE Trials
  Journal Scan:	Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial

• ALTITUDE
  Title:	ALTITUDE
  Year:	2011 (Media Release)

• ANTIPAF
  Title:	Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation
  Year:	2011

  Summary Slide(s):	ANTIPAF Trial Summary Slide
  Journal Scan:	Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF)-Trial

• CaVenT
  Title:	Catheter-Directed Venous Thrombolysis
  Year:	2011

  Summary Slide(s):	CaVenT Summary Slide
  Clinical Trial:	Thrombus Obliteration by Rapid Percutaneous Endovenous Intervention in Deep Venous Occlusion
  Journal Scan:	Long-Term Outcome After Additional Catheter-Directed Thrombolysis Versus Standard Treatment for Acute Iliofemoral Deep Vein Thrombosis (the CaVenT Study): A Randomised Controlled Trial

• Esomeprazole vs. Famotidine in Prevention of GI Bleeding in ACS or MI
  Title:	Esomeprazole Compared With Famotidine in the Prevention of Upper Gastrointestinal Bleeding in Patients With Acute Coronary Syndrome or Myocardial Infarction
  Year:	2011

  Summary Slide(s):	Esomeprazole vs. Famotidine Summary Slide
  Cardiosource Video News:	Marfans, Invasive Strategy, PPI Benefit
  Clinical Trial:	Clopidogrel and the Optimization of Gastrointestinal Events Trial

• LIPSIA-NSTEMI
  Title:	Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI
  Year:	2011

  Summary Slide(s):	LIPSIA-NSTEMI Summary Slide
  Cardiosource Video News:	Marfans, Invasive Strategy, PPI Benefit

• CLEVER
  Title:	Claudication: Exercise Versus Endoluminal Revascularization
  Year:	2011

  Summary Slide(s):	CLEVER Summary Slide
  Clinical Image:	CLEVER Presentation Slides
  Clinical Image:	CLEVER Discussant Slides
  Journal Scan:	Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study

• ELEVATE-TIMI 56
  Title:	Escalating Clopidogrel by Involving a Genetic Strategy–Thrombolysis In Myocardial Infarction 56
  Year:	2011

  Summary Slide(s):	ELEVATE-TIMI 56 Summary Slide
  Clinical Image:	ELEVATE-TIMI 56 Presentation Slides
  Clinical Image:	ELEVATE-TIMI 56 Discussant Slides
  Clinical Trial:	Gauging Responsiveness with A VerifyNow Assay—Impact on Thrombosis And Safety
  Journal Scan:	Dosing Clopidogrel Based on CYP2C19 Genotype and the Effect on Platelet Reactivity in Patients With Stable Cardiovascular Disease
  Cardiosource Video News:	ELEVATE-TIMI 56

• COPPS POAF
  Title:	Colchicine for the Prevention of the Post-Pericardiotomy Syndrome Atrial Fibrillation Substudy
  Year:	2011

  Summary Slide(s):	COPPS POAF Summary Slide
  Clinical Image:	COPPS POAF Presentation Slides
  Clinical Image:	COPPS POAF Discussant Slides
  Clinical Trial:	COlchicine for the Prevention of the Post-pericardiotomy Syndrome
  Journal Scan:	Colchicine Reduces Postoperative Atrial Fibrillation: Results of the Colchicine for the Prevention of Postpericardiotomy Syndrome (COPPS) Atrial Fibrillation Substudy

• EASE
  Title:	Randomized Trial of Early Surgery Versus Conventional Treatment for Infective Endocarditis
  Year:

  Summary Slide(s):	EASE Summary Slide
  Clinical Image:	EASE Presentation Slides

• SATURN
  Title:	Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin
  Year:	2011

  Summary Slide(s):	SATURN Summary Slide
  Clinical Image:	SATURN Presentation Slides
  Cardiosource Video News:	Hostility, SATURN, ESC Guidelines
  Journal Scan:	Effect of Two Intensive Statin Regimens on Progression of Coronary Disease

• Evacetrapib Dose Ranging Study
  Title:	Lipid-Modulating Effects of Evacetrapib, a Novel CETP Inhibitor, Administered as Monotherapy or in Combination With the Most Commonly Used Statins
  Year:	2011

  Summary Slide(s):	Evacetrapib Summary Slide
  Clinical Image:	Evacetrapib Dose Ranging Study Presentation Slides
  Clinical Image:	Evacetrapib Dose Ranging Study Discussant Slides
  Journal Scan:	Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial
  Cardiosource Video News:	Evacetrapib Results

• AIM-HIGH
  Title:	Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes
  Year:	2011

  Summary Slide(s):	AIM-HIGH Summary Slide
  Clinical Image:	AIM-HIGH Presentation Slides (AHA 2011)
  Clinical Image:	AIM-HIGH Discussant Slides (AHA 2011)
  Cardiosource Video News:	AIM-HIGH Stopped: No Benefit of Niacin
  Clinical Trial:	Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial
  Clinical Trial:	Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events
  Clinical Trial:	Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6–HDL and LDL Treatment Strategies
  Clinical Trial:	Action to Control Cardiovascular Risk in Diabetes Lipid Trial
  Journal Scan:	Niacin in Patients With Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

• ALPHEE
  Title:	Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator Interventions or Death
  Year:	2011

  Summary Slide(s):	ALPHEE Summary Slide
  Clinical Image:	ALPHEE Presentation Slides
  Clinical Image:	ALPHEE Discussant Slides
  Clinical Trial:	Increased Mortality After Dronedarone Therapy for Severe Heart Failure
  Journal Scan:	Efficacy and Safety of Celivarone, With Amiodarone as Calibrator, in Patients With an Implantable Cardioverter-Defibrillator for Prevention of Implantable Cardioverter-Defibrillator Interventions or Death: The ALPHEE Study

• MANTRA-PAF
  Title:	The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation
  Year:

  Summary Slide(s):	MANTRA-PAF Summary Slide
  Clinical Image:	MANTRA-PAF Presentation Slides
  Clinical Image:	MANTRA-PAF Discussant Slides

• PALLAS
  Title:	Permanent Atrial fibriLLAtion Outcome Study Using Dronedarone on Top of Standard Therapy
  Year:	2011

  Summary Slide(s):	PALLAS Summary Slide
  Clinical Image:	PALLAS Presentation Slides
  Clinical Image:	PALLAS Discussant Slides
  Journal Scan:	Dronedarone in High-Risk Permanent Atrial Fibrillation

• FAST
  Title:	Atrial Fibrillation catheter Ablation Versus Surgical Ablation Treatment
  Year:	2011

  Summary Slide(s):	FAST Summary Slide
  Clinical Image:	FAST Presentation Slides
  Clinical Image:	FAST Discussant Slides
  Journal Scan:	Atrial Fibrillation Catheter Ablation Versus Surgical Ablation Treatment (FAST): A 2-Center Randomized Clinical Trial

• MI FREEE
  Title:	Post-Myocardial Infarction Free Rx Event and Economic Evaluation
  Year:	2011

  Summary Slide(s):	MI FREEE Summary Slide
  Clinical Image:	MI FREEE Presentation Slides
  Clinical Image:	MI FREEE Discussant Slides
  Journal Scan:	Full Coverage for Preventive Medications After Myocardial Infarction

• HOOPS
  Title:	Heart Failure Optimal Outcomes From Pharmacy Study
  Year:

  Clinical Image:	HOOPS Presentation Slides
  Clinical Image:	HOOPS Discussant Slides

• CPORT E
  Title:	Atlantic Cardiovascular Patient Outcomes Research Team−E Trial
  Year:

  Summary Slide(s):	CPORT E Summary Slide
  Clinical Image:	CPORT E Presentation Slides
  Clinical Image:	CPORT E Discussant Slides
  Clinical Trial:	Atlantic Cardiovascular Patient Outcomes Research Team Trial

• ATLAS ACS 2-TIMI 51
  Title:	Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects with Acute Coronary Syndrome–Thrombolysis in Myocardial Infarction 51
  Year:	2011

  Summary Slide(s):	ATLAS ACS 2-TIMI 51 Summary Slide
  Clinical Image:	ATLAS ACS 2-TIMI 51 Presentation Slides
  Clinical Image:	ATLAS ACS 2-TIMI 51 Discussant Slides
  Clinical Trial:	Anti-Xa Therapy to Lower cardiovascular events in addition to Aspirin with or without thienopyridine therapy in Subjects with Acute Coronary Syndrome–Thrombolysis In Myocardial Infarction 46
  Clinical Trial:	Apixaban for Prevention of Acute Ischemic and Safety Events
  Clinical Trial:	Apixaban for Prevention of Acute Ischemic Events 2
  Clinical Trial:	Regulation of Coagulation in Orthopedic Surgery to Prevent Deep Venous Thrombosis and Pulmonary Embolism 1
  Clinical Trial:	Regulation of Coagulation in Orthopedic Surgery to Prevent Deep Venous Thrombosis and Pulmonary Embolism 2
  Clinical Trial:	Regulation of Coagulation in Orthopedic Surgery to Prevent Deep Venous Thrombosis and Pulmonary Embolism 3
  Clinical Trial:	Regulation of Coagulation in Orthopaedic Surgery to Prevent Deep Vein Thrombosis and Pulmonary Embolism 4
  Clinical Trial:	Safety, Tolerability, and Efficacy of Darexaban (YM150) in Patients With Acute Coronary Syndrome
  Journal Scan:	Rivaroxaban in Patients With a Recent Acute Coronary Syndrome

• AIDA STEMI
  Title:	Abciximab Intracoronary versus intravenously Drug Application in ST-Elevation Myocardial Infarction
  Year:

  Summary Slide(s):	AIDA STEMI Summary Slide
  Clinical Image:	AIDA STEMI Presentation Slides
  Clinical Image:	AIDA STEMI Discussant Slides